Article ID Journal Published Year Pages File Type
3391001 Seminarios de la Fundación Española de Reumatología 2012 6 Pages PDF
Abstract
Regional osteoporosis is similar in semiology and progression to severe diseases, such as avascular necrosis, and a similar mechanism in which regional osteoporosis would only be a stage in progression cannot be discarded. There is a scattered increase of resorption, which creates multiple regions of fragility where microfractures accumulate and bone fragility increases. Diagnosis requires clinical suspicion, which should lead to correct diagnosis in both forms. Treatment is symptomatic and, if possible, is based on the release of load. The use of anti-resorptives, and particularly of bisphosphonates, is limited during pregnancy, since these drugs pass the placenta. In both forms, restitution is progressive and relatively rapid after delivery.
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