| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3391612 | Seminars in Immunology | 2010 | 10 Pages |
Abstract
NKT cells are known to play a role against certain microbial infections, including malaria and HIV, two major global infectious diseases. NKT cells exhibit either protective or pathogenic role against malaria. They are depleted by HIV infection and have a direct pathogenic role against many opportunistic infections common in end-stage AIDS. This review discusses the various features of the interaction between NKT cells and malaria parasites and HIV, and the potential to harness this interaction for therapeutic and vaccine strategies.
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Authors
Sandhya Vasan, Moriya Tsuji,