Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3392491 | Transplant Immunology | 2007 | 5 Pages |
Abstract
We report a case of disseminated toxoplasmosis following heart transplantation in a Toxoplasma seropositive recipient before transplantation (R+) (IgG 1:160, IgM negative) who received an organ from a Toxoplasma seropositive donor (D+) (IgG 1:640, IgM negative). No anti-Toxoplasma prophylactic treatment was administered. A number of complications arose in the postoperative period, as well as Enterobacter cloacae and Cytomegalovirus (CMV) (reactivation) infections, but neither serological nor histological toxoplasma recrudescence was evidenced. The patient died on post transplant day 41. Post-autopsy histological examinations revealed an unexpected diffuse toxoplasmosis (lungs, brain, heart).
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Authors
Marta Castagnini, Sonia Bernazzali, Chiara Ginanneschi, Bruna Marchi, Massimo Maccherini, Charilaos Tsioulpas, Piero Tanganelli,