Article ID Journal Published Year Pages File Type
3393521 Travel Medicine and Infectious Disease 2007 6 Pages PDF
Abstract

BackgroundCertain activities expose travellers to Coxiella burnetii, the causative agent of acute human Q fever. Awareness of Q fever must be improved, also as a potential imported disease, but delayed seroconversion and serological cross-reactivity complicate the diagnosis. Granulomatous inflammation of liver and bone marrow can be typical histopathological findings.Case presentationsWe present three imported cases of Q fever with different clinical presentations, in which the travel history identified the sources of infection.ConclusionsQ fever should be suspected in any imported febrile disease of unknown origin. Clinical manifestations are variable and repeated serological testing is mandatory. In some cases diagnostic biopsies might help to establish early diagnosis.

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