Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3393589 | Travel Medicine and Infectious Disease | 2007 | 4 Pages |
Abstract
SummaryIn this open randomized trial comparing 3-day oral quinine–clindamycin versus standard mefloquine regimen for uncomplicated imported falciparum malaria, mefloquine treatment was associated with a higher risk of discontinuation of the treatment (RR=1.8, 95% CI [1.1–2.8]) related to mainly mild gastrointestinal adverse drug events. The poor tolerability of mefloquine sets a question mark against its use in outpatients.
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Authors
Stéphane Ranque, Philippe Parola, Eric Adehossi, Philippe Brouqui, Jean Delmont,