Article ID Journal Published Year Pages File Type
3394144 Acta Tropica 2010 7 Pages PDF
Abstract

The intracellular trafficking of an Erythrocyte Binding Like (EBL) ligand has recently been shown to dramatically affect the multiplication rate and virulence of the rodent malaria parasite Plasmodium yoelii yoelii. In this review, we describe the current understanding of the role of EBL and other erythrocyte binding ligands in erythrocyte invasion, and discuss the mechanisms by which they may control multiplication rates and virulence in malaria parasites.

Related Topics
Life Sciences Immunology and Microbiology Parasitology
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