Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3395969 | Antibiotiques | 2010 | 7 Pages |
Abstract
Carbapenems are being increasingly used because of the widespread dissemination of antibiotic resistance among Gram-negative bacilli, especially of extended-spectrum beta-lactamases; this increasing use raises the concern of loss of activity for this antimicrobial class following the emergence of carbapenemases. The current guideline from the Anti-infective drugs Committee of the Assistance publique-Hôpitaux de Paris (AP-HP) group emphasizes the careful and limited use of carbapenems, comparing the respective characteristics of the four available molecules, and specifies their indications in clinical hospital practice, with possible alternatives.
Keywords
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Authors
R. Gauzit, L. Gutmann, C. Brun-Buisson, V. Jarlier, B. Fantin, pour la commission des anti-infectieux de l'Assistance publique-Hôpitaux de Paris pour la commission des anti-infectieux de l'Assistance publique-Hôpitaux de Paris,