Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3396145 | Antibiotiques | 2007 | 5 Pages |
Abstract
This study evaluates the prevalence of the resistance of E. coli against amoxicillin-clavulanic acid (AMC), and analyzed the results according to the susceptibility testing methods. Strains tested with the ATB Expression were more resistant than with the E-test or the reference agar dilution methods, resulting in an apparent high frequency of resistance for E. coli. The rate of E. coli resistant to AMC is low: 3.2% and 2% for strains isolated from urinary tract (UT) and gastrointestinal tract (GIT). Moreover, 67% of the strains with reduced susceptibility had MICs ⤠8 mg/L. The percentage of resistance to nalidixic acid, norfloxacin and ciprofloxacin were 17.9%, 11.3% and 10.6% for the UT strains and 5%, 8.5% and 5.1% for the GIT strains, respectively. Considering the increase of fluoroquinolone resistance, AMC remains a useful antibiotic for the treatment of E. coli infections.
Keywords
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Infectious Diseases
Authors
M. Roussel-Delvallez, M. Caillaux, C. Cattöen, A. Decoster, D. Descamps, N. Graveline, S. Hendricx, M. Menouar, M.N. Noulard, J.G. Paul, M.P. Pelletier, C. Rolland, S. Samaille, A. Vachée, M. Vasseur, A. Verhaeghe, F. Delpierre, F. Wallet,