| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3400284 | Egyptian Journal of Chest Diseases and Tuberculosis | 2012 | 5 Pages |
IntroductionTuberculous pleural effusion (TPE) is a common problem for differential diagnosis from malignant effusion (MPE) in epidemic areas of tuberculosis (TB). Prediction based on adenosine deaminase (ADA) is dependent on age as well as the tuberculosis incidence.Aim of the workTo estimate the value of cutoff point of ADA in MPE and TPE & to evaluate its role in differential diagnosis in Egypt a country with high incidence of TB.Subjects & methodsThe study was conducted in Kaser El-Aini Hospital, Cairo University in the period from April 2011 to January 2012. It was carried on 30 patients. We retrospectively analyzed 30 patients with a definitive diagnosis of TPE (n = 19) and MPE (n = 11). The optimal cutoff value of ADA was determined using the receiver operating characteristic (ROC) curve. There was a statistically significant difference according to the levels of pleural fluid ADA between TPE and MPE groups.ResultConfirm that ADA is a very useful parameter for the differential diagnosis of TPE and MPE, specifically in younger with a higher incidence of tuberculosis.
