Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3407123 | Journal of Virological Methods | 2010 | 4 Pages |
Abstract
A variant specific direct loop-mediated isothermal amplification (LAMP) method was developed to detect human herpesvirus-6 (HHV-6) variants in serum samples. Specific primers were designed against HHV-6 U86 gene. Initial validation analysis confirmed high specificity and sensitivity of the method. This method was shown to be highly reliable for monitoring active HHV-6 infection in hematopoietic stem cell transplant recipients.
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Authors
Masaru Ihira, Hiroko Sugiyama, Yoshihiko Enomoto, Yuki Higashimoto, Ken Sugata, Yoshizo Asano, Tetsushi Yoshikawa,