Article ID Journal Published Year Pages File Type
3407310 Journal of Virological Methods 2010 4 Pages PDF
Abstract

The use of HIV-1 DNA quantitation in cellular reservoirs to predict disease progression and treatment outcome in infected patients is hampered by the lack of standardization among the available methods. In the present study, real-time PCR methods used commonly for HIV-1 proviral DNA evaluation were compared, showing strong differences in the results, probably as a consequence of genome variability in the target regions. Standardization of HIV-1 proviral DNA quantitation assays is needed for use in clinical management of patients with HIV-1.

Related Topics
Life Sciences Immunology and Microbiology Virology
Authors
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