Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3407783 | Journal of Virological Methods | 2008 | 4 Pages |
Abstract
We describe a simple Perl computer tool for matching successive subsequences of a query sequence using the BLAST facilities of Genbank. SWeBLAST helps identify ‘parents’ of recombinant sequences, even when these are themselves unrelated, thus it is complementary to methods that compare sets of aligned homologous sequences, and avoids the significant problem of these methods in having first to decide which sequences to compare. SWeBLAST searches may also be valuable for checking the recombination history of genes proposed for use as transgenes.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Virology
Authors
Mathieu Fourment, Adrian J. Gibbs, Mark J. Gibbs,