Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3407788 | Journal of Virological Methods | 2008 | 5 Pages |
Abstract
Rapid diagnosis of novel emerging subtypes of influenza viruses is vital for effective global influenza surveillance. To this end, a novel microarray based surveillance was developed for subtyping all influenza A viruses on one chip. Using reference strains of different influenza subtypes and samples from different areas, the results show that all the subtypes of the influenza A virus could be identified simultaneously on this microchip with high sensitivity. There was no cross-hybridization reaction with other viruses, indicating that the microarray is specific for influenza A viruses. Such a diagnostic microarray will undoubtedly be useful for identifying novel influenza A virus subtypes.
Keywords
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Virology
Authors
Xueqing Han, Xiangmei Lin, Bohua Liu, Yihong Hou, Jinhai Huang, Shaoqiang Wu, Jian Liu, Lin Mei, Guangle Jia, Qingyu Zhu,