| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 340831 | Seizure | 2007 | 5 Pages |
Abstract
SummaryWe studied the effects of high doses of pentobarbital (PB) and carbamazepine (CBZ) on electrolyte levels and pH in an epileptic animal model. Pentobarbital decreased Ca2+ and Na+ levels without pentylenetetrazole (PTZ). After this, Ca2+ and Na+ levels continued to decrease except when CBZ was used, which preserved the Ca2+ levels PTZ may have opposed effects on PB. Our results suggest that PB causes changes in electrolyte levels and pH, but these changes are diminished by CBZ.
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Authors
R. Uribe-Escamilla, D. Mota-Rojas, P. Sánchez-Aparicio, M. Alonso-Spilsbury, R. González-Piña, A. Alfaro-Rodríguez,