| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3414842 | Microbes and Infection | 2013 | 8 Pages |
Abstract
NLRs play fundamental roles in host-defense and inflammatory disorders. NLRP6 is a newly characterized member of this family that inhibits NF-κB and MAP-kinase dependent immune signaling to hamper anti-microbial defense. Further, NLRP6 regulates intestinal inflammation by maintaining gut microbiota composition. In this review, we examine the recent studies and emphasize the key functions regulated by NLRP6.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Paras K. Anand, Thirumala-Devi Kanneganti,