Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3414920 | Microbes and Infection | 2011 | 7 Pages |
Abstract
Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.
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Authors
Yu-Ping Chang, Chia-Ling Chen, Su-O Chen, Yee-Shin Lin, Cheng-Chieh Tsai, Wei-Ching Huang, Chi-Yun Wang, Chia-Yuan Hsieh, Pui-Ching Choi, Chiou-Feng Lin,