Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3414953 | Microbes and Infection | 2011 | 13 Pages |
Abstract
The introduction of a new influenza strain into human circulation leads to rapid global spread. This review summarizes innate and adaptive immunity to influenza viruses, with an emphasis on T-cell responses that provide cross-protection between distinct subtypes and strains. We discuss antigenic variation within T-cell immunogenic peptides and our understanding of pre-existing immunity towards the pandemic A(H1N1) 2009 strain.
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Authors
Sophie A. Valkenburg, John A. Rutigliano, Ali H. Ellebedy, Peter C. Doherty, Paul G. Thomas, Katherine Kedzierska,