| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3414987 | Microbes and Infection | 2011 | 11 Pages |
Abstract
The genomes of herpesviruses establish latency as a circular episome. However, Human herpesvirus-6 (HHV-6) has been shown to specifically integrate into the telomeres of chromosomes during latency and vertically transmit through the germ-line. This review will focus on the telomere integration of HHV-6, the potential viral and cellular genes that mediate integration, and the clinical impact on the host.
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Authors
Jesse H. Arbuckle, Peter G. Medveczky,