Article ID Journal Published Year Pages File Type
3415047 Microbes and Infection 2009 7 Pages PDF
Abstract

Crohn's Disease (CD) is caused by a loss of the regulatory capacity of the immune apparatus. Nod2 is an intracellular bacterial sensor and its mutations are associated with the development of CD. Here we summarize recent and controversial findings about the role of the Nod2 mutants in the disease process.

Related Topics
Life Sciences Immunology and Microbiology Immunology
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