Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3415047 | Microbes and Infection | 2009 | 7 Pages |
Abstract
Crohn's Disease (CD) is caused by a loss of the regulatory capacity of the immune apparatus. Nod2 is an intracellular bacterial sensor and its mutations are associated with the development of CD. Here we summarize recent and controversial findings about the role of the Nod2 mutants in the disease process.
Keywords
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Immunology
Authors
Soichiro Yamamoto, Xiaojing Ma,