Article ID Journal Published Year Pages File Type
3415049 Microbes and Infection 2009 7 Pages PDF
Abstract

AIRE is the gene responsible for a rather rare hereditary type of autoimmune disease. The mechanism underlying the autoimmune pathogenesis caused by AIRE deficiency is a focus of intense research because it could provide clues to the fundamental question of how the immune system discriminates between self and non-self within the thymic microenvironment.

Related Topics
Life Sciences Immunology and Microbiology Immunology
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