Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3415049 | Microbes and Infection | 2009 | 7 Pages |
Abstract
AIRE is the gene responsible for a rather rare hereditary type of autoimmune disease. The mechanism underlying the autoimmune pathogenesis caused by AIRE deficiency is a focus of intense research because it could provide clues to the fundamental question of how the immune system discriminates between self and non-self within the thymic microenvironment.
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Authors
Mitsuru Matsumoto,