| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3415060 | Microbes and Infection | 2011 | 12 Pages |
Abstract
Type I IFNs (IFNα/β) are essential anti-viral cytokines produced in response to the detection of viral components by host pattern recognition receptors. IFNα/β production is transient, and aberrant activation can be hazardous to the host. In this article, we review our current understanding of host negative regulatory mechanisms that control IFNα/β production.
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Authors
Kathryn H. Richards, Andrew Macdonald,