| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3415090 | Microbes and Infection | 2010 | 9 Pages |
Abstract
Interleukin-21 (IL-21) is a cytokine that has broad effects on both innate and adaptive immune responses. The roles of IL-21 in determining immunity to infections are currently being defined, and notably, it has been shown that IL-21 is most critical for sustaining T cell responses during chronic viral infections. This article discusses our current understanding of the immunobiology of IL-21, as well as its known and potential roles in influencing immunity to infections.
Keywords
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Immunology
Authors
John S. Yi, Maureen A. Cox, Allan J. Zajac,