| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3415094 | Microbes and Infection | 2010 | 9 Pages |
Abstract
Myxoma virus (MYXV) is a poxvirus with a strict rabbit-specific host-tropism for pathogenesis. The immunoregulatory factors encoded by MYXV can suppress some functions of immune effectors from other species. We review their mechanisms of action, implications in therapeutics and the potential to improve MYXV as an oncolytic agent in humans.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Jia Liu, Sonia Wennier, Grant McFadden,