Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3415180 | Microbes and Infection | 2009 | 9 Pages |
Abstract
Programmed cell death is an essential mechanism of the host to combat infectious agents and to regulate immunity during infection. Consequently, activation and deactivation of the hosts' cell death pathways by protozoan parasites play critical roles in parasite control, pathogenesis, immune evasion and parasite dissemination within the host. Here, we discuss advances in the understanding of these fascinating host-parasite interactions with special emphasis on how protozoa can modulate the cell death apparatus of its host.
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Authors
Kristin Graumann, Diana Hippe, Uwe Groß, Carsten G.K. Lüder,