Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3415485 | Microbes and Infection | 2009 | 9 Pages |
Abstract
Initially recognized in infection because of antimicrobial activity (‘tryptophan starvation’), indoleamine 2,3-dioxygenase (IDO) is widely involved in host immune homeostasis and even immune evasion by microbes that establish commensalism or chronic infection. This review deals with recent findings that could gain IDO a reputation of Jack-of-all-trades in mammalian host/microbe interactions.
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Authors
Teresa Zelante, Francesca Fallarino, Francesco Bistoni, Paolo Puccetti, Luigina Romani,