| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3415532 | Microbes and Infection | 2007 | 6 Pages |
Abstract
Tumor necrosis factor (TNF) is critical and non-redundant to control Mycobacterium tuberculosis infection and cannot be replaced by other proinflammatory cytokines. Overproduction of TNF may cause immunopathology, while TNF neutralization reactivates latent and chronic, controlled infection, which is relevant for the use of neutralizing TNF therapies in patients with rheumatoid arthritis.
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Authors
Muazzam Jacobs, Dieudonnée Togbe, Cecile Fremond, Arina Samarina, Nasiema Allie, Tania Botha, Daniela Carlos, Shreemanta K. Parida, Sergei Grivennikov, Sergei Nedospasov, Analbery Monteiro, Marc Le Bert, Valerie Quesniaux, Bernhard Ryffel,