Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3415538 | Microbes and Infection | 2007 | 5 Pages |
Abstract
CATERPILLER is a mammalian gene family with signature NBD and LRR domains. Several members of this family are positive regulators of inflammatory responses. Others, however, exert negative effects on proinflammatory responses. These data are particularly convincing when shRNA/siRNA are used. This review focuses on the Monarch-1/PYPAF7 gene with brief discussions of CLR16.2/NOD3, PYPAF2/PAN1/NALP2, and PYPAF3.
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Authors
John D. Lich, Jenny Pan-Yun Ting,