Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3416023 | Microbes and Infection | 2007 | 9 Pages |
Abstract
Natural resistance-associated macrophage proteins (Nramp) are multispecific symporters facilitating proton-dependent import of divalent metals. Nramp1 restricts microbial access to essential micro-nutrients such as iron and manganese within professional phagosomes. Increased understanding of Nramp1 roles in human phagocytes will be useful for future therapeutic approaches against selected infectious and immune diseases.
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Authors
Mathieu F. Cellier, Pascal Courville, Carole Campion,