Article ID Journal Published Year Pages File Type
3416023 Microbes and Infection 2007 9 Pages PDF
Abstract

Natural resistance-associated macrophage proteins (Nramp) are multispecific symporters facilitating proton-dependent import of divalent metals. Nramp1 restricts microbial access to essential micro-nutrients such as iron and manganese within professional phagosomes. Increased understanding of Nramp1 roles in human phagocytes will be useful for future therapeutic approaches against selected infectious and immune diseases.

Related Topics
Life Sciences Immunology and Microbiology Immunology
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