Article ID Journal Published Year Pages File Type
3416077 Microbes and Infection 2006 10 Pages PDF
Abstract

Apoptosis signal-regulating kinase 1 (ASK1) is a mitogen-activated protein kinase kinase kinase which plays pivotal roles in stress and immune responses. This review is focused on three major subjects on ASK1: the regulatory mechanisms of the kinase activity, the pathophysiological roles in stress response and innate immunity, and the evolutionary perspectives.

Related Topics
Life Sciences Immunology and Microbiology Immunology
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