Article ID Journal Published Year Pages File Type
3416106 Microbes and Infection 2007 8 Pages PDF
Abstract

Vaccination against pathogen toxins provides a rational approach to prevent morbidity and mortality, and is widely validated in the context of bacterial infections. A saccharide-conjugate vaccine targeting the malaria glycosylphosphatidylinositol toxin glycan could therefore prevent severe disease. This strategy could also reduce the risk posed by ‘rebound’ infections or immunopathology associated with other interventions.

Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
,