Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3419706 | Revue de Pneumologie Clinique | 2009 | 4 Pages |
Abstract
The authors report a rare case of low register systemic lupus erythematosus with renal attack and neurological armature by isoniazid. The patient was a 23-year-old woman presenting a lupus induced by isoniazid 1Â month after the treatment of pleural tuberculosis. Antinuclear antibodies, anti-native DNA, anti-ENA, anti-Sm, anti-SSa, anti-SSb and antihistone were present. The symptoms included arthralgia, fever, anaemia, pleural effusion, pericarditis and anasarca. She presented a renal and neurological attack, accounting for the gravity of the disease. The treatment consisted of the interruption of the isoniazid and a bolus of methyl-prednisolone during 3Â days relayed by an oral corticosteroid. The evolution was favourable after 8Â months of corticosteroids.
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Authors
J.L. Rakotoson, D. Randriamanana, J.R. Rakotomizao, R. Andrianasolo, R. Rakotoarivelo, A.C.F. Andrianarisoa,