Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3420050 | Revue de Pneumologie Clinique | 2008 | 4 Pages |
Abstract
Peripheral neuroectodermal tumors constitute a large spectrum of small round cell tumors amoung which Ewing's sarcoma is the most indifferentiated type. They are rare tumors which often concern young people and generally occur in bone tissue. Their metastatic potential is high, generally early, and rarely after five years. We report the case of a 45-year-old woman who presented a mediastinal metastasis eight years after the primitive tumor of tibia. The diagnosis was made on small core biopsies obtained by CT ponction, and was based on morphologic analysis, immunohistochemistry, and confirmed by molecular biology. The presence of metastasis is the main prognostic factor. Despite therapeutic progress, the global survival rate of metastatic patients is still poor.
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Authors
A. Cremades, C. Tériitéhau, B. Grand, P. Saint-Blancard,