| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3423610 | Trends in Parasitology | 2006 | 6 Pages |
Abstract
Filarial nematodes persist in the parasitized host by modulating immune responsiveness. A feature of this that has been observed in a multitude of studies dating back several decades is an inability of lymphocytes to respond appropriately to filarial nematode antigens and, in some cases, to other stimuli. The consistency of this observation, allied to the ease of measurement of lymphocyte hyporesponsiveness, has resulted in many attempts to understand its cause.
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Authors
William Harnett, Margaret M. Harnett,