Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3426247 | Virology | 2007 | 6 Pages |
Abstract
A virus-dependent fusion assay was utilized to examine the activity of a panel of HIV-1, -2, and SIV isolates of distinct coreceptor phenotypes. This assay allowed identification of entry inhibitors, and characterization of an antagonist of a Rac guanine nucleotide exchange factor, as an inhibitor of HIV-mediated fusion.
Related Topics
Life Sciences
Immunology and Microbiology
Virology
Authors
Suzanne Pontow, Brooke Harmon, Nancy Campbell, Lee Ratner,