Article ID Journal Published Year Pages File Type
3428032 Virus Research 2015 4 Pages PDF
Abstract

•Lagos bat virus was isolated from a straw-coloured fruit bat (Eidolon helvum) from Ghana.•Phylogenetically the virus was classified as member of lineage A.•Conspecifics of the colony had neutralizing antibodies (74% of 567 animals) when the homologous virus was used as test virus, but not using a different Lagos bat virus (lineage B).

A brain sample of a straw-coloured fruit bat (Eidolon helvum) from Ghana without evident signs of disease tested positive by generic Lyssavirus RT-PCR and direct antigen staining. Sequence analysis confirmed the presence of a Lagos bat virus belonging to phylogenetic lineage A. Virus neutralization tests using the isolate with sera from the same group of bats yielded neutralizing antibodies in 74% of 567 animals. No cross-neutralization was observed against a different Lagos bat virus (lineage B).

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Life Sciences Immunology and Microbiology Virology
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