Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3428724 | Virus Research | 2012 | 5 Pages |
Abstract
Cryo-electron microscopy was applied to analyze mud crab reovirus (MCRV), which causes ‘sleeping disease’ in mud crab, Scylla serrata, a marine species cultured in China. We present here the three dimensional structure of MCRV at 13.8 Å resolution. The outer capsid shell is composed of 260 trimers with complete T = 13 icosahedral symmetry. A major difference between MCRV and previously reported aquareoviruses is that it lacks a pentameric turret structure. These results together with recently published molecular biological evidence (Deng et al., 2012) indicate that, from a structural perspective, MCRV should be classified as a new member of the family Reoviridae.
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Virology
Authors
Zengwei Huang, Xiexiong Deng, Yinyin Li, Hongjun Su, Kunpeng Li, Zhixun Guo, Peirui Zheng, Haidong Xu, Jianguo He, Qinfen Zhang, Shaoping Weng,