| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3431470 | Virus Research | 2006 | 4 Pages |
Abstract
RNA silencing is a natural defense response against viral infection. This phenomenon has been used to interfere with viral infections by exploiting fragments of viral genomes as sources of RNA silencing. Agrobacterium-mediated transient expression of a hairpin RNA derived from the TGBp1 gene of Potato virus X (PVX) induced RNA silencing of the TGBp1 gene and resulted in interference of PVX infection. The interference was induced in the infiltrated leaves but not in the upper non-infiltrated leaves. Transient expression of a CP hairpin RNA also induced interference of PVX. The TGBp1 hairpin RNA showed more efficient interference of PVX infection than the CP hairpin RNA.
Related Topics
Life Sciences
Immunology and Microbiology
Virology
Authors
Shuichiro Takahashi, Ken Komatsu, Satoshi Kagiwada, Johji Ozeki, Takuma Mori, Hisae Hirata, Yasuyuki Yamaji, Masashi Ugaki, Shigetou Namba,