Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3432131 | American Journal of Obstetrics and Gynecology | 2016 | 9 Pages |
Abstract
Risk assessment of infected fetuses for being symptomatic at birth is possible as early as the time of diagnosis by using a combination of targeted ultrasound examination along with viral load in amniotic fluid and in fetal blood together with platelet count. The advantage of using amniotic fluid is that it is available at prenatal diagnosis. One may wonder if increasing the negative predictive value of the overall assessment of an infected fetus from 95-100% is worth the additional risk of cordocentesis for fetal blood sampling. This can only be an individual decision made by well-informed women and it seems therefore appropriate to use the figures presented here and their confidence intervals for counseling.
Related Topics
Health Sciences
Medicine and Dentistry
Medicine and Dentistry (General)
Authors
Marianne MD, Julien MD, Yann MSc, Tiffany BA, Anne MSc, Jean-François MD, Sophie MD, François MD, Yves MD,