Cystatin A protease inhibitor and cysteine proteases in human cervicovaginal fluid in term pregnancy and labor

In late gestation, CVF-decreased expression of the cysteine protease inhibitor, cystatin A, is associated with labor. Although the role and contribution of cystatin A to increased extracellular matrix remodeling has yet to be elucidated, the data that were obtained are consistent with this hypothesis.