Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3439090 | American Journal of Obstetrics and Gynecology | 2007 | 6 Pages |
Abstract
This study outlines protease-activated receptor-4 messenger RNA and protein expression in human myometrium. Protease-activated receptor-4 activation exerts a mild uterotonic effect, whereas protease-activated receptor-4 antagonism results in a mild uterorelaxant effect. The potent human uterotonic effect of thrombin is not apparently mediated to any great extent by protease-activated receptor-4.
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Authors
Nicholas M. MB, BSc, Margaret PhD, Anne M. PhD, Terry J. PhD, John J. MD,