| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3439943 | American Journal of Obstetrics and Gynecology | 2008 | 16 Pages |
Abstract
Proteomics-based characterization of urine in preeclampsia identified a proteomic fingerprint composed of SERPINA1 and albumin fragments, which can accurately diagnose preeclampsia and shows promise to discriminate it from other hypertensive proteinuric diseases. These findings provide insight into a novel pathophysiological mechanism of preeclampsia related to SERPINA1 misfolding, which may offer new therapeutic opportunities in the future.
Related Topics
Health Sciences
Medicine and Dentistry
Medicine and Dentistry (General)
Authors
Irina A. MD, Guomao BSc, Edmund F. MD, Nathan MSc, Isaac E. MD, Ira M. MD, George R. MD, Catalin S. MD,