Is there a therapeutic impact to regional lymphadenectomy in the surgical treatment of endometrial carcinoma?

This study emphasizes the importance of lymph node dissection in endometrial cancer. Lymph node dissection is essential for accurate surgical staging, which remains the most important prognostic factor. In addition to well-known clinicopathologic risk factors for survival, the removal of 10 or more regional lymph nodes was associated with improved overall survival in lower-stage, older patients who received no adjuvant therapy or brachytherapy only.