Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3447414 | Archives of Medical Research | 2007 | 8 Pages |
Abstract
The study showed a good correlation and concordance between the ploidy distribution by cytogenetics and flow cytometry. The patterns of chromosomal anomalies in our patients showed some variations in the frequency of aberrations reported. It is therefore necessary that newer techniques like fluorescence in situ hybridization (FISH) along with reverse transcriptase polymerase chain reaction (RT-PCR) and spectral karyotyping will help us identify chromosomal aberrations not detected by conventional cytogenetic methods in the near future. To our knowledge, this is the first report from the Middle East of a cytogenetic study on childhood ALL.
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Authors
Achandira Muthappa Udayakumar, Wafa Ahmed Bashir, Anil Vasant Pathare, Yasser Ahmed Wali, Mathew Zacharia, Ashfaq Ahmed Khan, Heba Soliman, Zakia Al-Lamki, John Alexander Raeburn,