Active-Assisted Cycling Improves Tremor and Bradykinesia in Parkinson's Disease

Ridgel AL, Peacock CA, Fickes EJ, Kim C-H. Active-assisted cycling improves tremor and bradykinesia in Parkinson's disease.ObjectivesTo develop a rapid cadence cycling intervention (active-assisted cycling [AAC]) using a motorized bike and to examine physiological perimeters during these sessions in individuals with Parkinson's disease (PD). A secondary goal was to examine whether a single session of AAC at a high cadence would promote improvements in tremor and bradykinesia similar to the on medication state.DesignBefore-after pilot trial with cross-over.SettingUniversity research laboratory.ParticipantsIndividuals with idiopathic PD (N=10, age 45–74y) in Hoehn and Yahr stages 1 to 3.InterventionForty minutes of AAC.Main Outcome MeasuresHeart rate, pedaling power, and rating of perceived exertion were recorded before, during, and after a bout of AAC. Functional assessments included tremor score during resting, postural, and kinetic tremor.ResultsThis AAC paradigm was well tolerated by individuals with PD without excessive fatigue, and most participants showed improvements in tremor and bradykinesia immediately after a single bout of cycling.ConclusionsThis paradigm could be used to examine changes in motor function in individuals with PD after bouts of high-intensity exercise.