Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3451112 | Archives of Physical Medicine and Rehabilitation | 2009 | 14 Pages |
Abstract
Twenty-three studies met inclusion criteria. Thirteen studies examined various pharmacologic interventions for the treatment or prevention of deep venous thrombosis in patients with SCI. There was strong evidence to support the use of low-molecular-weight heparin in reducing venous thrombosis events, and a higher adjusted dose of unfractionated heparin was found to be more effective than 5000 units administered every 12 hours, although bleeding complications were more common. Nonpharmacologic treatments were also reviewed, but again limited evidence was found to support these treatments.
Keywords
PEDroAPTTIVCUFHIPCRCTLMWHS/CRandomized controlled trialAsiaSpinal cord injuriesSpinal cord injuryPulmonary embolismAmerican Spinal Injury AssociationVenous thrombosisDVTDeep venous thrombosisRehabilitationcomputed tomographyactivated partial thromboplastin timesubcutaneoussciintermittent pneumatic compressionunfractionated heparinlow-molecular-weight heparininternational unitsInferior vena cava
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Authors
Robert W. MD, FRCPC, Jane T. MSc, Jo-Anne L. BA, Janice J. PhD, Andrei MD, PhD, FRCPC, Linh HonBHSc, Spinal Cord Injury Rehabilitation Evidence Review Research Team Spinal Cord Injury Rehabilitation Evidence Review Research Team,