Convexity of Scoliosis Related to Handedness in Identical Twin Boys With Duchenne's Muscular Dystrophy: A Case Report

The interplay between hand dominance and directionality of scoliosis in boys with Duchenne's muscular dystrophy (DMD) is not clearly defined. We describe an extremely rare presentation of monozygotic twin boys with DMD and opposing hand dominance who developed major spine curvature with opposite convexities. The unique clinical presentation of progressive neuromuscular disease and scoliosis in monozygotic twins should allow for a unique evaluation of some of the contributory factors associated with the development of neuromuscular scoliosis in DMD. In this case report, we explore the pathophysiology involved in neuromuscular scoliosis, examine the role of conservative, surgical, and medical treatments, and discuss potential future avenues of research.