Quantitative Histology and Ultrastructure Fail to Explain Weakness of Immobilized Rabbit Achilles' Tendons

Our results add to the recent literature about the absence of characteristic histologic or collagen fibril size markers that could explain the mechanical weakness of immobilized tendons. Further research using biochemical, gene expression, and functional imaging markers of tendon is needed to pinpoint the alterations responsible for the mechanical weakness. Such markers would be crucial for the rehabilitation and secondary prevention of tendon injuries.