Arsenic induced histological alterations in testis of Swiss albino mice and protection by Chlorophytum borivilianum

ObjectiveTo investigate the sodium arsenite induced damages on the reproductive system of male mice as well as to examine whether Chlorophytum borivilianum (C. borivilianum) is able to ameliorate the damages.MethodsA different group of adult Swiss albino mice was made such as control group, sodium arsenite group, post combination group, pre and post combination group. After the treatment, the testis was removed, weighed and processed for histopathological observation. Cauda epididymis was used to observe abnormal sperms.ResultsA highly significant depletion was found in all the germ cell populations such as spermatogonia A and B, primary and secondary spermatocytes, spermatids in arsenic treated group with respect to control whereas recovery is found in combination groups.ConclusionsThe results conclude that C. borivilianum significantly protects against arsenic-induced damages.