Effect of Evolvulus alsinoides on lipid metabolism of streptozotocin induced diabetic rats

ObjectiveTo determine the effect of ethanolic extract of Evolvulus alsinoides (E. alsinoides) on diabetes-induced changes in lipid metabolism.MethodsThe ethanolic extract of E. alsinoides on serum and tissue lipid levels were examined in control and experimental group rats.ResultsOral administration of E. alsinoides extract to streptozotocin induced diabetic rats for 45 d significantly reduced the levels of triglycerids, phospholipids, cholesterol and free fatty acids in serum and tissues, it increases the high density lipoprotein in serum as that of control.ConclusionsThe ethanolic extract of E. alsinoides supplementation is useful in hyperlipidemia prevention during diabetes mellitus.