Article ID Journal Published Year Pages File Type
3454997 Asian Pacific Journal of Tropical Disease 2014 4 Pages PDF
Abstract

ObjectiveTo evaluate the larvicidal efficacy of crude petroleum ether, chloroform, acetone and aqueous aerial extracts of Cleome viscosa against the filarial vector, Culex quinquefasciatus.MethodsStandard World Health Organization protocols with minor modifications was adopted for the larvicidal bioassay. Larvicidal activity of exyracts was evaluated at concentrations of 62.5, 125, 250, 500 and 1 000 mg/L. Larval mortality was observed after 24 and 48 h.ResultsAmongst the solvent extracts tested, petroleum ether exhibited the highest larvicidal activity and LC50 values was 52.62 and 43.16 mg/L followed by acetone, aqueous and chloroform extract with LC50 values of 328.64 and 280.58; 493.44 and 298.76; 509.27 and 434.40 mg/L after 24 and 48 h respectively.ConclusionsFurther investigations are needed to explore the larvicidal activity of the petroleum ether aerial extract of this plant against a wide range of mosquito species and also the active ingredient(s) of the extract responsible for larvicidal activity should be identified.

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